OH.

MY.

GOD.

Poor, poor Karkat, that’s a lot to have on your shoulders. Such a small mistake, such huge ramifications, and he’s so young. 

But now the question is, does the scratch replicate the cancer? If it’s restarting to its initial state, the universe would still be lacking that important code, so it would still be ultimately barren, unless our heroes find a way to fix it.